It is based on the core module of pharmacy syllabi of various technical universities and targets undergraduate and postgraduate students across India. It is based upon the latest developments in the field of medicinal chemistry, detailed synthesis mechanism of drugs and their mode of action inside the body. This book treats many aspects of organic medicinal compounds; their discovery, action, and development into clinical agents. All the principles discussed in the book are based on fundamental organic chemistry, physical chemistry and biochemistry.Medicinal chemistry plays a key role in pharmaceutical research and new drug discovery; the structural modification may help in increasing the potency of desired active and/or to decrease the intensity of adverse effects. This book attempts to present a review of basic principles of medicinal chemistry and to explain the effects of structural modification of the lead nucleus on the selectivity of action, duration of action and frequency of adverse effect. An effort has been made to stress upon basic pharmacology in detail wherever needed.
Anurekha Jain, MPharm, PhD
Currently serving as a Professor at TIT College of Pharmacy in Bhopal, Dr. Anurekha Jain is a distinguished community awareness expert, social entrepreneur, CEO, and academician. She has an extensive academic background, having worked for 13 years as a Professor and Research Associate at the TIFAC-Center of Relevance and Excellence in Green Pharmacy, under the Ministry of Science and Technology, Government of India, at BR Nahata College of Pharmacy. She also served as the Principal of the same institution for two years.
Dr. Jain held the position of Dean of the Department of Pharmaceutical Sciences at Jayoti Vidyapeeth Women University in Jaipur, Rajasthan, and has also been the Director of Innovare Academic Sciences, where she led initiatives in online education, intellectual property rights services, and research publications.
With over 100 research papers published in national and international journals, along with 28 review articles, 5 books, and 4 patents, Dr. Jain has made significant contributions to the field. She has delivered numerous invited talks, chaired various scientific sessions, and served as a judge at multiple national seminars and conferences.
Malleshappa N. Noolvi, MPharm, PhD
Professor, Department of Pharmaceutical Chemistry
Shree Dhanvantary Pharmacy College, Surat, Gujarat
Dr. Malleshappa N. Noolvi received his PhD in 2006 from Rajiv Gandhi University of Health Sciences, Bangalore. He has over 14 years of experience in teaching, research, and development. He has published more than 30 scientific papers and review articles in reputed international journals. His major research interests include QSAR studies, molecular docking, synthesis of novel anticancer agents, and analytical method development for improved selectivity and sensitivity in quantitative drug analysis. He is widely recognized for his expertise in medicinal and pharmaceutical chemistry and for his innovative teaching methods.
Harun M. Patel, MPharm, PhD
Department of Pharmaceutical Chemistry
R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur (Dhule), Maharashtra
Dr. Harun M. Patel has published around 30 research papers in reputed peer-reviewed international journals. His research interests include QSAR studies, molecular docking, virtual screening, and the synthesis of novel anticancer, antitubercular, and antiepileptic agents.
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