The understanding of genetic diseases has improved a great deal in recent decades, benefiting from the revolutionary discoveries being made in genetics and genomics. This book seeks to present the latest themes, issues and challenges from the field to inform and inspire specialist readers. Part one considers studies in population genetics. New findings are offered on topics such as the evolution of plant mating systems, and population genetics in the genomics era. Part two presents new insights into topics including the therapeutic role of haematopoietic stem cells in osteogenesis imperfecta, and structural insights into disease mutation of the ryanodine receptor. Part three focuses on human genetic diseases, and includes studies of the development, physiology and pathophysiology of the FGF family in humans and other species, and osteoclast genetic diseases. Finally, part four presents advances in the study of genetic disorders, and offers new findings on alpha-1-antitrypsin deficiency, and Fabry disease. This cutting-edge text offers a wealth of findings and fresh perspectives from the forefront of the field.
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