The processes and mechanisms of DNA repair have been a subject of fascination and intense research for decades. This new book aims to bring the reader an up-to-date picture of current research topics and challenges through expert studies from around the world. Part one focuses on DNA repair and human health. Topics examined here include DNA mismatch repair genes and endometrial cancer, and the relationship between DNA damage and energy metabolism. Part two considers new research directions in DNA repair. Here, studies address issues such as emerging features of DNA double-strand break repair in humans, and the intriguing relationship between DNA repair and telomeres. Part three examines the pathways to fixing DNA damage and errors. Here, contributors focus on topics including lagging strand synthesis and genomic stability, and DNA repair in embryonic stem cells. Finally, part four presents further selected studies on topics including interactions of carcinogenic metal compounds with DNA repair processes, and DNA helix destabilization by alkylating agents. This wide-ranging collection is an excellent resource for readers seeking to update their knowledge in this fast-developing field.
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