This book integrates
various scientific disciplines, including biology, toxicology, pharmacology,
theoretical chemistry, microbiology and biopharmacy within the field of
medicinal chemistry, which is an exciting and dynamic field that plays a
crucial role in drug discovery and development. This book is the result of 30
years of teaching and engaging with graduate students across multiple
universities. The encouragement from faculty and students for the earlier works
has motivated the authors to present the second edition of the popular book.
Designed as a comprehensive yet accessible
resource, this book follows the latest syllabus set forth by the Pharmacy
Council of India, catering specifically to undergraduate students preparing for
Medicinal Chemistry I. This volume comprises twelve chapters covering essential
topics such as the history and development of medicinal chemistry,
physicochemical properties, metabolism, and various classes of drugs, including
adrenergic, cholinergic, sedatives, antipsychotics, anticonvulsants, narcotics,
and anti-inflammatory agents. Each chapter provides a clear introduction, classification
with examples, structure–activity relationships (SAR), detailed information on
individual drugs including structure, IUPAC names, mechanisms of action, uses,
and selected synthesis to facilitate student understanding
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