This is a widely appreciated text on the subject. Primarily meant for BPharm students, this textbook is also useful for MPharm, BSc and MSc students studying organic chemistry and pharmaceutical chemistry. It aims at eliminating the inadequacies in teaching and learning of medicinal chemistry by providing valuable information on the most relevant topics. The text adequately covers the latest syllabi of Pharmacy Council of India (PCI) and all major Indian Universities. The fourth edition features new layout and design in an attractive two-color presentation.
Salient Features Serves as a unique and valuable textbook containing completely updated information on medicinal chemistry, adapting to the latest/revised syllabus prescribed by Pharmacy Council of India (PCI). Presents clear classification, synthetic schemes, mode of action, metabolism, assay, pharmacological uses with the dose and structure–activity relationship (SAR) of the drugs for the various body systems. Carries a complete section on drug design, describing the new drug development. Discusses briefly physiological and pathophysiological conditions of diseases and their treatment. Provides well-illustrated synthetic schemes and alternative synthetic routes for majority of drugs that help in quick and enhanced understanding of the subject. Explains physicochemical parameters with related information; includes two new chapters •Protein binding Biotransformation or metabolism of drugs added in this edition. Features new chapters like •Pharmacophore modeling •Docking and antisense technology given under the section of drug design Embraces PCI syllabus-based classification of drugs for easy to study and write in examination. Incorporates updated information on several newer drugs in different chapters in consonance with the revised PCI syllabus. Serves as an excellent companion for the GPAT aspirants.
V Alagarsamy MPharm,PhD,FIC,DOMH is Professor and Principal,MNR College of Pharmacy,and Director,MNR Foundation for Research and Innovation, Gr. Hyderabad, Telangana. He received his DPharm from Coimbatore Medical College, BPharm from Madurai Medical College, MPharm from LM College of Pharmacy, Ahmedabad, and PhD from The MS University, Baroda. He has been teaching medicinal chemistry and conducting research work in synthetic medicinal chemistry on novel heterocyclic bioactive compounds for more than two decades. For his research work he has been collaborated with various research laboratories/organizations like National Cancer Institute, USA; Rega Institute for Medical Research, Belgium; Southern Research Institute, USA; and Sudbury Regional Hospital, Ontario, Canada. He is a recipient of young scientist project from Department of Science and Technology,New Delhi.He is the author/co-author of over 200 papers, which include the original research articles and presentations in various conferences and symposiums, having one patent for his credit on bioactive heterocyclic molecule. He is the co-editor of the international journal Antiinfective Agents, published by Bentham Science Publishers. His books Textbook of Medicinal Chemistry, Pharmaceutical Chemistry of Natural Products, Pharmaceutical Inorganic Chemistry, Organic Chemistry: A Comprehensive Approach, Pharmaceutical Organic Chemistry and Practical Pharmaceutical Inorganic Chemistry are well appreciated in the academic community nationally and received international recognition too. His research activities are supported by the funding agencies like CSIR,DST and DSIR. Prof Alagarsamy is a member of All India Board of Pharmaceutical Education (AIB-PE),AICTE, New Delhi,and a member of board of studies (pharmacy) in Osmania University, Hyderabad, and is a doctoral committee member and a recognized research guide for PhD scholars in various universities. Recently, he has been named among top 2% scientists in the world in the field of pharmacy by Stanford University,USA